The neural drive to a muscle refers to the net output of all the motoneurons that innervate the muscle. Neural drive is also used in the context of the neural drive to the motoneuron pool, which refers to the net synaptic input to the motoneurons from different areas of the central nervous system.

The synaptic connection between an axon terminal of a motoneuron and a skeletal muscle fibre.The neuromuscular junction consists of a presynaptic motor axon terminal, a postsynaptic motor endplate on the muscle fibre and the synaptic cleft between the axon terminal and the motor endplate.